TriaLink MEA EDGE

Specially designed to recreate different cellular microenvironment for co-culture of 3 different cell types with fluidic isolation.

Each chips are compartmentalized by microchanels technology.This enables co-culture of different cell types (microbiota, neurons & intestinal cells or astrocytes, dosal horn & sensory neurons...). Microchhanels technology enables also innervation of the 3rd channel by neuron endings. By adding the MEA option, record the electrical activity of neurons to decode data from any innervated organ.

Up to 16 data points, TriaLink is composed of 3 compartments for independant culture per chips​ and 1 compartment for fluidic isolation and and cell type electrophysology activity isolation per compartment & remote stimulation. The µchannels technology are used to compartmentalize culture and connect channels.

TECHNICAL SPECIFICATION
1 2
  • Functional activity recording
  • Up to 3 cell types electrophysiology activity isolation per compartment
  • Compatible with Maestro EDGE or PRO, powered by Axion BioSystems
  • 2 QuarterBentos (8 data points)
  • 1 NeoBento MEA EDGE with 2 plugs
  • UpLink, utility software, downloadable from on support page
1.950,00€
1.950,00€
Sale Sold out
Shipping calculated at checkout.
View full details

Features.

  • High-Throughput Format.

    NeoBento™, the standard format for NeuroPlatforms chips, available up to 4 QuarterBentos™ (up to 16 chips).

    • Standard ANSI format (96-well plate)
    • Pump-free & expensive equipment-free
    • Standard equipment (liquid handling & imaging) compatibility

  • Readouts Compatibility.

    In-depth reading of the data to better understand the study results and potential implications.

    • Electrophysiological recording (MEA)
    • Imaging (Immunofluorescence, Calcium Imaging…)​
    • Biochimic analysis (ELISA, Lysis cells analysis, Liquid Chromatography…)​

  • Compartmentalization.

    Compartmentalized microfluidics devices to co-culture 2 different cell types.

    • Each compartment has its own media & coating solutions
    • Discrimination of mode and mechanism of action
    • Pathophysiological applications

  • Innervation Of Any Organ.

    Microchannels technology allow only the passage of neuron endings leaving cell bodies in compartment. .

    • Microbiota-Gut-Brain Axis
    • Microbiota digital signature
    • Depression
TECHNOLOGY IN DEPTH