DuaLink Well MEA EDGE

Specially designed to monitor the functional activity of innervated 3D organoids, compatible with Maestro PRO or EDGE (Axion BioSystems).

Each chips are composed of channels and open well and compartmentalized by microchanels technology.This enables co-culture of different 2D and 3D cell types (innervated liver, innervated lung…). By adding the MEA option, record the electrical activity of neurons to decode data from any innervated organoids.

Up to 16 data points, DuaLink Well MEA is composed of 2 channels for 2D culture & fluidic isolation and 1 open well for 3D culture and cell type electrophysology activity isolation per compartment & remote stimulation. The µchannels technology are used to compartmentalize culture and connect channels to open well.

TECHNICAL SPECIFICATION
1 2
  • Innervated 3D Culture
  • Functional activity recording
  • 2 cell types (2D, 3D or biopsy) electrophysiology activity isolation per compartment
  • Compatible with Maestro EDGE or PRO, powered by Axion BioSystems
  • 2 QuarterBentos (8 data points)
  • 1 NeoBento MEA EDGE with 2 plugs
  • UpLink, utility software, downloadable from on support page
1.950,00€
1.950,00€
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Features.

  • High-Throughput Format.

    NeoBento™, the standard format for NeuroPlatforms chips, available up to 4 QuarterBentos™ (up to 16 chips).

    • Standard ANSI format (96-well plate)
    • Pump-free & expensive equipment-free
    • Standard equipment (liquid handling & imaging) compatibility

  • Readouts Compatibility.

    In-depth reading of the data to better understand the study results and potential implications.

    • Electrophysiological recording (MEA)
    • Imaging (Immunofluorescence, Calcium Imaging…)​
    • Biochimic analysis (ELISA, Lysis cells analysis, Liquid Chromatography…)​

  • Compartmentalization.

    Compartmentalized microfluidics devices to co-culture 2 different cell types.

    • Each compartment has its own media & coating solutions
    • Discrimination of mode and mechanism of action
    • Pathophysiological applications

  • Innervation Of Any Organ.

    Microchannels technology allow only the passage of neuron endings leaving cell bodies in compartment. .

    • Innervated 3D Liver organoid
    • Innervated 3D Lung organoid
    • Innervated 3D Brain organoid
TECHNOLOGY IN DEPTH