DuaLink Shift MEA PRO

Specially designed monitor the functional activity of synapses and co-culture up to 2 cell types (glutamatergic & GABAergic neurons…).

Each chips are compartmentalized by microchannels technology.This enebles the creation of axodendritic synapses in the 2nd channel and the monitoring of axonal growth kinetics. Microchhanels technology enables also co-culture of different cell types (NMJ, GABAergic neurons & glutamatergic neurons…). By adding the MEA option, record the electrical activity of synapses, isolated per compartment.

Up to 16 data points, DuaLink Shift MEA is composed of 2 compartments for independant culture per chips​ and 1 compartment for synapses isolation and synapses electrophysology activity isolation per compartment & remote stimulation. The µchannels technology are used to compartmentalize culture and connect channels.

TECHNICAL SPECIFICATION
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  • Functional activity recording
  • Synaptic activity recording and directionality
  • Compatible with Maestro PRO, powered by Axion BioSystems
  • 4 QuarterBentos (16 data points)
  • 1 NeoBento MEA PRO
  • UpLink, utility software, downloadable from on support page
2.990,00€
2.990,00€
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Features.

TECHNOLOGY IN DEPTH

  • High-Throughput Format.

    NeoBento™, the standard format for NeuroPlatforms chips, available up to 4 QuarterBentos™ (up to 16 chips).

    • Standard ANSI format (96-well plate)
    • Pump-free & expensive equipment-free
    • Standard equipment (liquid handling & imaging) compatibility

  • Readouts Compatibility.

    In-depth reading of the data to better understand the study results and potential implications.

    • Electrophysiological recording (MEA)
    • Imaging (Immunofluorescence, Calcium Imaging…)​
    • Biochimic analysis (ELISA, Lysis cells analysis, Liquid Chromatography…)​

  • Compartmentalization.

    Compartmentalized microfluidics devices to co-culture 2 different cell types.

    • Each compartment has its own media & coating solutions
    • Discrimination of mode and mechanism of action
    • Pathophysiological applications

  • Innervation Of Any Organ.

    Microchannels technology allow only the passage of neuron endings leaving cell bodies in compartment. .

    • Neuroinflammation
    • Inflammatory Bowel Disease
    • Huntington’s disorders

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TECHNOLOGY IN DEPTH